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This thesis analyses the impact of announcements of macroeconomic indicators in United States on price development of the VIX Futures, S&P500 Futures and EUR/USD FX rate. Theoretical part contains construction and description of individual markets. Empirical part investigates the reaction of market prices after 1, 10 and 30 minutes after announcement of an individual indicator value on a market surprise demonstrated as a difference between reported value and analysts’ expectations. We tried to find a systematic reaction of market participants and the pace of absorption of new information into the market price. There have been found minimum of situations, where we explained the market move as a linear combination of market surprise. However, there was a several cases, where the market did not adjust to announced information quickly and was inefficient in a short period. In the second part of empirical research we tested all significant models on an out-sample data. The goal was to determine whether the market inefficiencies persisted and stable profit could be achieved. We analysed the brutto performance, then netto performance including all transaction costs. Finally, we defined a simple trading rules with a purpose of profit stabilization and lowering the riskiness of trades. For VIX Futures and EUR/USD markets we achieved a low loss, respectively negligible profit. For S&P 500 Futures we obtained a profit strategies for all selected indicators, total profit was high with a very low volatility of invested capital.